You are probably defining/using an input for some safetyfeature or something, maybe worldzones. If it would be possible to edit the value by hand or from the rapid things could go wrong.
For this the I/O must be set to acces level “read only” in the I/O signal definenition.
To do this go to:
control panel
Configuration
I/O
Signals
Select the signal in question and edit the acces level to “Read Only”