How to change status I/O signals on the OPC UA Client side?

OPC Client connected to the IRC5 OPC UA Server, I got I/O status signals, but I am not able to change the state of any I/O item. Any help is appreciated.

Hi, im just curious
What do you use as a OPC Client?

It does not matter. It is just OPC industrial protocol. You can use any or develop by yourself.

It works, sorry. Problem was in Security Policy